Oolong Tea means “black dragon” tea in Chinese, a name that does justice to its boldness and drama. This traditional Chinese tea undergoes a unique process, including withering under the strong sun and oxidation before curling and twisting. Oolongs range between 8% and 85% oxidized, which results in a wide range of colors and aromas. The flavor of oolongs is equally diverse: they can be smoky, sweet and fruity, woody and thick , or green and fresh.
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For additional help, contact our .Effects of oolong tea on gene expression of gluconeogenic enzymes i...
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):930-8. doi: 10.1089/jmf.. Epub
2011 Aug 3.Effects of oolong tea on gene expression of gluconeogenic enzymes in the mouse liver and in rat hepatoma H4IIE cells.1, , , , , , .1Health Care Research Center, Nisshin Pharma Inc., Fujimino, Saitama, Japan.AbstractTea has many beneficial effects. We have previously reported that green tea and a catechin-rich green tea beverage modulated the gene expression of the gluconeogenic enzymes glucose-6-phosphatase (G6Pase) and phosphoenolpyruvate carboxykinase (PEPCK) in the normal murine liver. In the present study, we examined the effects of oral administration of oolong tea on the hepatic expression of gluconeogenesis-related genes in the mouse. The intake of oolong tea for 4 weeks reduced the hepatic expression of G6Pase and PEPCK together with that of the transcription factor hepatocyte nuclear factor (HNF) 4α. When rat hepatoma H4IIE cells were incubated in the presence of oolong tea, the expression of these genes was repressed in accordance with the findings in vivo. The reduced protein expression of PEPCK and HNF4α was also demonstrated. We then fractionated oolong tea by sequential extraction with three organic solvents to give three fractions and the residual fraction (Fraction IV). In addition to organic fractions, Fraction IV, which was devoid of low-molecular-weight catechins such as (-)-epigallocatechin gallate (EGCG), had effects similar to those of oolong tea on H4IIE cells. Fraction IV repressed the gene expression of insulin-like growth factor binding protein 1, as insulin did. This activity was different from that of EGCG. The present findings suggest that drinking oolong tea may help to prevent diabetes and that oolong tea contains a component or components with insulin-like activity distinguishable from EGCG. Identification of such component(s) may open the way to developing a new drug for diabetes.PMID:
[PubMed - indexed for MEDLINE]
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